| F5 | CYP2D6 | G6PD | CYP2C9 | CYP4F2 | VKORC1 | CYP2C19 | SLCO1B1 |
| Steps | Accuracy |
|---|---|
| DNA sequencing | 99.9% |
| Variant calling – SNP | >99%*# |
| Variant calling – Indel | >99%*# |
* Passed GenQA/UK NEQAS external quality assurance
# The interpretation of sequencing variants is based on the current understanding of the variants at the time it was observed, which may change over time as more information about the genes becomes available. Not all variants are represented in this report.
Disclaimer:
The interpretations and clinical annotations provided by
Codex are intended solely for use by a medical professional and do not
constitute medical advice by Codex. Test results shown on this report
require clinical interpretation and comments by a specialist of the
respective discipline. The pharmacokinetics of a drug might be affected by
the dosage form and route of administration. Please consult a qualified
healthcare professional before making decisions about medical conditions or
before starting and stopping any prescribed treatment. The treating
providers are ultimately responsible for all diagnoses and treatments. The
report and recommendations are based on the guidelines provided by CPIC1 and
do not take into account other genetic variants and environmental or social
factors that may affect the drug response. Other factors not included in
this report include, but are not limited to, environmental factors (e.g.,
smoking), health factors (e.g., diet), social factors, various medical
conditions, and other concurrent medications. Off-label drug uses are not
considered in this report. The recommendations in the report are for the
corresponding drugs only, and the drug-drug interactions are not considered.
As a matter of practice, Codex will routinely update its database as new
information becomes available to the scientific community. Annotations and
recommendations are therefore dependent on the date of generation and/or the
database version used to generate that report.
